Huntington's disease: underlying molecular mechanisms and emerging concepts
نویسندگان
چکیده
منابع مشابه
Huntington's disease: underlying molecular mechanisms and emerging concepts.
Huntington's disease (HD) is a progressive neurodegenerative disorder for which no disease modifying treatments exist. Many molecular changes and cellular consequences that underlie HD are observed in other neurological disorders, suggesting that common pathological mechanisms and pathways may exist. Recent findings have enhanced our understanding of the way cells regulate and respond to expand...
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ژورنال
عنوان ژورنال: Trends in Biochemical Sciences
سال: 2013
ISSN: 0968-0004
DOI: 10.1016/j.tibs.2013.05.003